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Platelet rich plasma is concentrated blood plasma that contains, around, five times the number of platelets found in normal circulating blood. In addition, blood plasma contains the growth factors PDGF and VEGF and other bioactive proteins that aid in wound healing. This plasma concentrate can accelerate wound healing and tissue repair and, thus, could potentially benefit hair restoration procedures. To obtain PRP, a patient’s blood is spun in a centrifuge that separates the "solid" from "liquid" components. The separated “solid” portion of the blood is PRP (platelet rich plasma). This PRP is then placed into a syringe and reintroduced into the site of injection. In hair transplantation, PRP can be injected into the recipient site area to stimulate the healing of the transplanted grafts and into the donor area to facilitate healing of the donor incision.
Platelet Rich Plasma (PRP) is a blood serum with a heavy concentration of platelets. The exact amount varies by how it is processed, but quality ranges a drastic amount. PRP, to be effective, must have a high concentration of platelets, growth factors like PDGF, and cytokines.
As a treatment, PRP is used often used in medicine for quicker healing and better tissue repair, particularly sports medicine. Clinical studies range in endorsing PRP, however, because its production is not standardized though it nearly always
PRP is typically produced through devices that centrifuges the patient's blood, dividing platelets and other materials from the blood to concentrate it. The treatment is also combined with an activator, such a saline or calcium gluconate, to open the growth factor's alpha granules. Both the centrifugation and activator is why effectiveness can range so dramatically.
Dr. Cole has done specific research into the effectiveness of PRP. Evidence shows that the growth factor and cytokine count matters tremendously. Using two kits that led to different concentrations of growth factors, Dr. Cole found the one with significantly greater growth factors led to a 50% increase in hair density while the one with less growth factors led to a 25% decrease in hair density.
Further experimentation with processing led to Dr. Cole using sonication within a soundproof box. The results, what Forhair calls Cytokine Rich Plasma (CRP), has five to eight times the amount of growth factors and cytokines. Results are also unprecedented. Transplant patients who received the treatment enjoyed 99% follicular activation within four and a half months; more than double the rate of transplant patients who did not receive CRP.
PRP and CRP also have a longer duration with the addition of ACell, making the treatment more cost-effective. ACell + PRP or CRP lasts between half a year and a year while maintaining PRP's effect alone requires injections every month or season. PRP and CRP are great with transplants but also as standalone treatments. Learn more on our CRP and PRP page!