|
Dr. Cole and Dr. Jimenez are beginning a study looking at the follicular
sheath for evidence of stem cells. One way to look for stem cells is to look for
CD34. CD34 is known as hematopoietic progenitor cell antigen and is thought to
be a marker for stem cells. The tissue will be immunostained with a monoclonal
antiCD34 antibody. There are flase positives for this stanin as it can react
with endothelial cells, as well. It has been demonstrated in the bulge of mice
and outer root sheath in the past though it is not as easy delineate the
location of the bulge in humans. The value of this study will be to provide
evidence that very well trimmed grafts produced by follicular isolation contain
the stem cells necessary to produce new growth. It may also provide more data
for our hair multiplication efforts. Of further interest is that CD34 has been
shown in embryonic messenchymal cells that are associated with epithelial germ
cell placodes.
We recently removed back hair from a patient who had the back treated with
laser hair removal devices multiple times. The hair re-grew on his back despite
multiple treatments with the laser. This was fortuitous, however. The re-growth
has allowed him additional hair for the top of his scalp since his scalp donor
hair is virtually depleted. If he had know about the capacity to perform body
hair transplants sooner, he would not have treated his hairy body with laser
hair removal and he would have had even more hair for the top of his
head.
|